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Levocetirizine comes under Antihistamine – Drug class, which treat the symptoms of seasonal allergies, allergic rhinitis, sore throat, and chronic Your healthcare professional may think taking both medications can relieve your allergy symptoms, so they may recommend taking Zyrtec 6 hours after taking Benadryl, which is how long Benadryl s effects last. If you take Zyrtec first, wait 24 hours before taking Benadryl. This can prevent potential adverse effects from worsening. Officially, it is not recommended to mix antihistamines unless recommended by the doctor, but it appears that they don’t really interact anyway. philith coupon Some people might tolerate one to two drinks while taking antihistamines, since alcohol tolerance can vary among different ages and sexes. Finding the best antihistamine for your symptoms can take a while. In the Antihistamines in this group include cetirizine (Zyrtec), loratadine Can You Take Zyrtec and Benadryl Together? According to Benadryl s website, It is never safe to take multiple antihistamine medications such as Zyrtec and Benadryl or Claritin and